Postdoctoral Researcher (m/f) 100%

In the field of rare metabolic liver diseases
4 years
Your responsibilities
Project background
Rare diseases affect 400 million people worldwide, and about 500,000 in Switzerland. Due to their usually early onset, rare diseases predominantly affect children and young adults. Since individually rare, those diseases are also called “orphan diseases”. Our research group works on metabolic liver diseases with a specific focus on defects of ureagenesis. We are using standard methodology (molecular genetics, protein biochemistry) as well as unique in-house developed stable isotope-based flux analyses when working with different test systems including protein, cellular and animal models.
This project is supported by the Swiss National Science Foundation as a collaboration with university groups in Basel and Lausanne.
  • You will work at the interface between the University Children's Hospital Zurich and the partner institutions.
  • The main responsibilities will include the familiarization and implementation of required methodologies before project start.
  • The goal is to contribute to the development of a novel therapeutic approach designed for treating metabolic liver diseases.
  • Specifically, the approach involves utilizing lipid nanoparticles carrying DNA expression plasmids for direct and long-lasting gene addition into hepatocytes.
  • Since this is a translational project, the aim is to test this new methodology first in cultured cells, then in an existing mouse model and finally, planned as a continuation project, a transfer into clinical practice.
  • You could also have the opportunity to participate in the planning and execution of clinical trials.
Your profile
  • You have already obtained a PhD in Biology or a related field,
  • You have experience with cell culture and animal work.
  • You have excellent communication skills (written and verbal) in English and be enthusiastic about working in a highly interdisciplinary environment of scientists, biologists, and clinicians.
  • You have a strong research track record.
  • Ideally you have solid experience in molecular genetics and protein biochemistry, prior experience with cellular and animal models.
  • You have an interest in rare disease and clinical translation.
  • You are driven, goal- and team-oriented.

Your salary

Your estimated gross salary for a 100% position should fall between CHF 91'000 and CHF 112'000 per year.

The exact salary will depend on your qualifications and professional experience. Your salary will be established in accordance with our salary guidelines during the selection process. Applicants who do not yet possess the necessary skills and experience may in some cases be offered a lower pay grade. In many cases, supplementary pay will be offered for irregular working hours. Further salary development will depend on your performance and the financial ability of the Eleonorenstiftung.

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Contact

Prof. Dr. med. Johannes Häberle
Leitender Arzt
johannes.haeberle@kispi.uzh.ch

Forschungszentrum für das Kind
Karin Asanin
HR Specialist Apply now
Your start with us
upon agreement

The application process

After you have submitted your application via our online portal, we will consider it carefully. We will make an initial selection from among the applications received and then get in touch with you. If we progress to the interview stage, the following procedure will apply:

application process

Your benefits

Leave the car at home.

All employees with at least 50% employment level and a contract duration of 6 months or longer benefit from CHF 500 discount per year on the SBB GA travel card or get at least 25% discount on the ZVV BonusPass for the entire ZVV network.

Mix your own smoothies.

Enjoy the healthy and tasty menu of the day in our staff restaurant for just CHF 9.00. With a varied salad buffet, juice bar, muesli bar and cake buffet, the restaurant caters for every taste.

Have you heard about the "Frauenbadi"?

Don’t worry – there’s a men’s one too! Located in the heart of Europe and right next to a lake, Zurich strikes the perfect balance between modern city life and stunning nature. Zurich is the education and economic centre of Switzerland and hosts countless events and a wide range of activities – there’s some-thing for everyone! More information about working in Switzerland can be found here.

We love all children - including yours!

We have signed a contract with the GFZ foundation day care centre, located near the Kispi, meaning you can benefit from longer day care at the same price. Your children can stay at the day care centre from 6:30 am to 6:30 pm.​

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We're also a hotel.

Recently moved to the city and haven’t found somewhere to live yet? Then rent one of our furnished staff bedrooms, located just a stone’s throw away from the hospital. Learn more.

We will help you through difficult times.

For all contracts at the Children’s Hospital with a level of employment of 20% or above, you benefit from our Visana accident insurance policy, that includes a worldwide private coverage for all accidents occurring while at work or during leisure time. In case your contract is below 20% employment level, accidents while on leisure are also covered in line with applicable law regulations.

Take a city break!

Every five years, you’ll be rewarded for your loyalty with extra holiday days. Previous roles at the Children’s Hospital will be counted.

Get well soon!

Have you worked for us for more than three months in at least a 0.2 FTE position? In most cases, you will benefit from Helsana daily sickness benefits insurance. In the event of illness, you will receive a daily allowance amounting to 80% of your salary for up to 720 days.

Head to the south!

If your five weeks of holiday aren’t enough, we’ll do our best to let you take unpaid holiday.

We fill your piggy bank

We assume 60% of your pension fund contributions, which exceeds the statutory minimum. As a part-time employee, you also benefit from a reduced coordination offset.

Spend more time with your children.

With interesting part-time roles available, we aim to give our employees the opportunity to balance their career with family life. For example, if you’ve just started a family or are finishing up a degree, you can look into reducing your working hours at the Children’s Hospital.

We'll update your vaccination record.

The staff doctor isn’t just there for emergencies – you can consult them about vaccinations and occupational health.

Let’s write history.

Join us and move with us to one of the most stunning and state-of-the art children’s hospitals. Herzog&De Meuron has developed something truly unique with the new children’s hospital in Zürich Lengg. Become part of it and let’s shape our future together.

Surpass yourself.

No matter what stage of your career you are at, the Children’s Hospital Zurich can help you go further. Our career models for nurses, doctors and in research offer you a huge variety of development opportunities for your specialist or management career.

Kinderspital Zürich as an employer
Kinderspital Zürich is the largest university children's hospital in Switzerland with about 2,500 employees, and is one of the leading centres for paediatric and youth medicine in Europe. Although the hospital may be big, it's the little ones that count: up to 100,000 patients are cared for each year across 47 faculties, where we do everything in our power to ensure their well being. 'Kispi' not only offers cutting-edge devices and the highest quality of care, but also a good sense of interpersonal issues. Alongside its comprehensive range of paediatric medicine and surgery facilities, the children's hospital also offers a unique rehabilitation centre and a research centre.

Your location

Steinwiesstrasse 75
8032 Zürich
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